Disease modeling Severe congenital neutropenia (CN) is a rare heterogeneous bone marrow syndrome characterized by maturation arrest of granulopoiesis at the level of promyelocytes/myelocytes, resulting in an absence of mature granulocytes in peripheral blood (neutropenia) and severe recurrent bacterial infections. So far, more than 20 different genes have been identified to be associated with CN, … Continue reading Disease modeling
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